Longevity from the Vertical Farm: The Science of Scarlet Bee Balm

At PhNova, we believe in merging tradition with the future of technology to create sustainable, high-quality ingredients for health. Our latest focus is on Monarda didyma, commonly known as Scarlet Bee Balm, a vibrant perennial from the mint family that is proving to be a powerhouse in the world of healthy aging.


The Vertical Farming Advantage

Botanical species are as extraordinary as they are fragile, with climate change posing a constant threat to the quality and availability of natural derivatives. To combat this, PhNova utilizes Vertical Farming to ensure:

  • Controlled Environments: We enable the cultivation of medicinal plants in a controlled environment, ensuring high quality standards and consistent performance.
  • Sustainability: Our innovative technology optimizes the use of natural resources and reduces the consumption of soil and water.
  • Purity: Botanicals obtained via vertical farming contain a high content of bioactive compounds and an unaltered, complete phytocomplex free of contaminants.

Our Key Areas of Expertise

Exosomes Nutra

Exosomes Nutra

Enhancing bioavailability and efficacy of active ingredients

Vertical Farming Botanics

Derived from food sources or natural ingredients
Superoxide Dismutase

Superoxide Dismutase

Nature’s Defense for Joints, Heart
and Skin
Aroma Neutra Food

Aroma Neutra & Food

Turning Innovation into Market-Ready Solutions

The Power of Didymin

The secret behind Scarlet Bee Balm’s efficacy lies in its rich phytocomplex of flavonoids and polyphenols, mainly located in the leaves and aerial parts. Specifically, it contains a natural flavonoid glycoside called didymin.

When consumed, didymin can be transformed in the intestine into isosakuranetin. This biologically active compound has been associated with the activation of the Nrf2/Keap1 pathway, an endogenous defense system that regulates antioxidant enzymes. This activation helps the body neutralize reactive oxygen species (ROS) and maintain redox balance, protecting DNA, proteins, and lipids from oxidative damage.


Scientific Breakthroughs in Healthy Aging

A landmark study from the University of Padua and Mibelle Group Biochemistry, published in GeroScience (2025), has unveiled the remarkable “geroprotective” potential of Scarlet Bee Balm extract.

Key Clinical Findings:

In a randomized, double-blind trial involving 81 participants between the ages of 45 and 65 with self-reported stressful jobs, the results after 12 weeks were significant:

  • Slowing Biological Age: People consuming the extract showed an increase in biological age of only 0.3 years, compared to 1.8 years for those in the placebo group.
  • DNA Protection: Supplementation significantly improved leukocyte telomere length (LTL) and stabilized DNA methylation age (DNAmAge).
  • Stress & Quality of Life: The extract reduced cortisol levels by 25% and improved measures of physical movement and sleep quality.

“Aging is a natural and inexorable process, but thanks to these results, we can say we have one more tool to counteract it and help people live better.” — Professor Sofia Pavanello.


Analytical Excellence

At PhNova, we standardize our Monarda didyma to ensure the highest potency for health ingredients. Our analytical specifications for Didimina (didymin) are verified through rigorous testing:

Parametro Metodo Valore
Didimina HPLC-DAD ≥ 2,00% p/p

Ready to bring the future of botanical science to your health products? Contact us to learn more about our high-quality Scarlet Bee Balm extract.

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FAQ's about Longevity from the Vertical Farm: The Science of Scarlet Bee Balm

What is Scarlet Bee Balm (Monarda didyma)?

Scarlet Bee Balm is a perennial plant belonging to the mint family (Lamiaceae) that is native to North America. It is characterized by a phytocomplex rich in flavonoids and polyphenols, specifically containing the natural flavonoid glycoside known as didymin.

Once consumed, didymin is transformed in the intestine into a biologically active compound called isosakuranetin. This compound activates the Nrf2/Keap1 pathway, an endogenous defense system that helps the body neutralize reactive oxygen species (ROS) and protects lipids, proteins, and DNA from oxidative damage.

The study found that participants taking the Scarlet Bee Balm extract (marketed as MonaJuventa Nu) experienced an increase in biological age of only 0.3 years over 12 weeks, compared to 1.8 years in the placebo group. It also significantly improved leukocyte telomere length (LTL) and stabilized DNA methylation age.

Yes. In a randomized trial of 81 people with self-reported stressful jobs, 12 weeks of supplementation reduced cortisol levels by 25%. Participants also reported a significant improvement in their overall Quality of Life (QOL), specifically regarding physical movement and sleep quality.

Vertical farming allows for the cultivation of medicinal plants in a fully controlled environment, which ensures consistent performance and high quality standards regardless of external climate change. This method also optimizes natural resources by significantly reducing the consumption of water and soil.

Yes. Because our botanicals are grown using innovative vertical farming technology, they provide a complete, unaltered phytocomplex that is naturally free of contaminants.

At PhNova, we use rigorous analytical testing to ensure potency. We standardize our extract to contain a minimum value of $\ge 2.00\%$ p/p of Didimina (didymin) using the HPLC-DAD method.

Get in Touch with PhNóva

Have questions or need expert guidance? Contact us today — our team is ready to assist you with tailored solutions for your formulations.

12/02/2026
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